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Article

Matrix metalloproteinase-1 polymorphism (-1607G) and disease severity in non-cystic fibrosis bronchiectasis in Taiwan.

PloS one - 1 Jan 2013

Hsieh Meng-Heng, Chou Pai-Chien, Chou Chun-Liang, Ho Shu-Chuan, Joa Wen-Ching, Chen Li-Fei, Sheng Te-Fang, Lin Horng-Chyuan, Wang Tsai-Yu, Chang Po-Jui, Wang Chun-Hua, Kuo Han-Pin

Abstract excerpt

OBJECTIVES: Bronchiectasis is characterized by an irreversible dilatation of bronchi and is associated with lung fibrosis. MMP-1 polymorphism may alter its transcriptional activity, and differentially modulate bronchial destruction and lung fibrosis. DESIGN: To investigate the association of MMP-1 polymorphisms with disease severity in non-cystic fibrosis (CF) bronchiectasis patients, 51 normal subjects and 113...

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Identifiers

PMID: 23776649
DOI: 10.1371/journal.pone.0066265
PMCID: PMC3679085

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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