Article
Living with genome instability: plant responses to telomere dysfunction.
Science (New York, N.Y.) - 2 Mar 2001
Riha K, McKnight T D, Griffing L R, Shippen D E
Abstract excerpt
Loss of telomere function in metazoans results in catastrophic damage to the genome, cell cycle arrest, and apoptosis. Here we show that the mustard weed Arabidopsis thaliana can survive up to 10 generations without telomerase. The last five generations of telomerase-deficient plants endured increasing levels of cytogenetic damage, which was correlated with developmental anomalies in both vegetative and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.