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Article

Modeling neural tube defects in the mouse.

Current topics in developmental biology - 1 Jan 2008

Zohn Irene E, Sarkar Anjali A

Abstract excerpt

Neural tube defects (NTDs) are among the most common structural birth defects observed in humans. Mouse models provide an excellent experimental system to study the underlying causes of NTDs. These models not only allow for identification of the genes required for neurulation, they provide tractable systems for uncovering the developmental, pathological and molecular mechanisms underlying NTDs. In addition, mouse...

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PMID: 19186242
DOI: 10.1016/S0070-2153(08)00601-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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