Article
Analysis of TGF-beta(1) gene polymorphisms in Hong Kong Chinese patients with asthma.
The Journal of allergy and clinical immunology - 1 Jan 2006
Mak Judith C W, Leung Helen C M, Ho Siu P, Law Barbara K W, Ho Alice S S, Lam Wah K, Ip Mary S M, Chan-Yeung Moira M W
Abstract excerpt
BACKGROUND: The C-509T polymorphism of TGF-beta(1) gene has been associated with asthma and atopy in white populations. OBJECTIVE: We investigated the association between asthma and previously identified polymorphisms at C-509T and T869C of the TGF-beta(1) gene among 250 Chinese patients with asthma and 308 healthy controls in Hong Kong. METHODS: Genotyping was performed on peripheral blood genomic DNA by using...
Topics
- Adult
- Aged
- Asthma
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Humans
- Logistic Models
- Male
- Middle Aged
- Polymorphism, Genetic
