Article
Relationship between polymorphisms in the TGF-β receptor gene and susceptibility towards chronic obstructive pulmonary disease in Northern Indians.
Expert review of respiratory medicine - 1 May 2026
Mahajan Nidhi, Chopra Vishal, Garg Kranti, Sharma Siddharth
Abstract excerpt
BACKGROUND: Chronic Obstructive Pulmonary Disease (COPD) is a multifactorial respiratory disorder influenced by genetic, environmental, and lifestyle factors such as smoking. The Transforming Growth Factor Beta Receptor 1 (TGFBR1) plays a crucial role in regulating cell proliferation, differentiation, apoptosis, and immune modulation. Dysregulation of TGFBR1 may disrupt downstream signalling, leading to chronic...
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