Article
Effects of single nucleotide polymorphisms 869 T/C and 915 G/C in the exon 1 locus of transforming growth factor-beta1 gene on chronic obstructive pulmonary disease susceptibility in Chinese.
Chinese medical journal - 20 Feb 2010
Liu Dai-shun, Li Xiao-ou, Ying Bin-wu, Chen Lei, Wang Tao, Xu Dan, Wen Fu-qiang
Abstract excerpt
BACKGROUND: The main risk factor for chronic obstructive pulmonary disease (COPD) is cigarette smoking. However, only 10% - 20% of chronic heavy smokers develop systematic COPD. We hypothesized that the inheritance of gene polymorphisms could influence the development of COPD, which was investiga...
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