Article
Transforming growth factor-beta1 gene polymorphisms associated with chronic obstructive pulmonary disease in Chinese population.
Acta pharmacologica Sinica - 1 Jun 2005
Su Zhi-guang, Wen Fu-qiang, Feng Yu-lin, Xiao Min, Wu Xiao-ling
Abstract excerpt
AIM: To determine the frequencies of polymorphism and haplotype in the transforming growth factor-beta 1 (TGF-beta1) gene promoter in the Chinese population and to investigate the susceptibility of this population to chronic obstructive pulmonary disease (COPD). METHODS: The target fragments of the TGF-beta1 gene promoter were amplified and analyzed by polymerase chain reaction-restriction fragment length...
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