Genetic polymorphisms and plasma levels of transforming growth factor-beta(1) in Chinese patients with tuberculosis in Hong Kong.

doi:10.1016/j.cyto.2007.09.006

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Article

Genetic polymorphisms and plasma levels of transforming growth factor-beta(1) in Chinese patients with tuberculosis in Hong Kong.

Cytokine - 1 Dec 2007

Mak Judith C W, Leung Helen C M, Sham Arthur S K, Mok Thomas Y W, Poon Yik N, Ling Sai O, Wong Ka C, Chan-Yeung Moira

Abstract excerpt

Susceptibility to tuberculosis (TB) may be affected by host genetic factors. Elevated levels of transforming growth factor-beta 1 (TGF-beta(1)) were found in plasma of patients with active TB compared with those of healthy contacts. To investigate the association of TGF-beta(1) gene polymorphisms (C-509T and T869C) and plasma levels with the risk of TB in Hong Kong Chinese adults, a case-control study was carried...

Topics

Adolescent
Adult
Aged
Asian People
Case-Control Studies
Child
Enzyme-Linked Immunosorbent Assay
Female
Genotype
Hong Kong
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Polymerase Chain Reaction

Polymorphism, Restriction Fragment Length

Polymorphism, Single Nucleotide

Transforming Growth Factor beta1

Tuberculosis, Pulmonary

Source

Open in PubMed

Identifiers

PMID: 18029191
DOI: 10.1016/j.cyto.2007.09.006

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