Article
Genetic polymorphisms and plasma levels of transforming growth factor-beta(1) in Chinese patients with tuberculosis in Hong Kong.
Cytokine - 1 Dec 2007
Mak Judith C W, Leung Helen C M, Sham Arthur S K, Mok Thomas Y W, Poon Yik N, Ling Sai O, Wong Ka C, Chan-Yeung Moira
Abstract excerpt
Susceptibility to tuberculosis (TB) may be affected by host genetic factors. Elevated levels of transforming growth factor-beta 1 (TGF-beta(1)) were found in plasma of patients with active TB compared with those of healthy contacts. To investigate the association of TGF-beta(1) gene polymorphisms (C-509T and T869C) and plasma levels with the risk of TB in Hong Kong Chinese adults, a case-control study was carried...
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