Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Biological characterization of long-term cultured human mesenchymal stem cells.

Archives of pharmacal research - 1 Jan 2009

Kim Jiseon, Kang Jin Wook, Park Jae Hyun, Choi Youngju, Choi Kyung Suk, Park Ki Dae, Baek Dae Hyun, Seong Su Kyoung, Min Hong-Ki, Kim Hyung Soo

Abstract excerpt

Human mesenchymal stem cells (hMSCs) have generated a great deal of interest in clinical applications. The reason is that they may have the plasticity needed to differentiate into multiple lineages and the ability to expand ex vivo. For the therapeutic applications of hMSCs to be of practical use, it is crucial to assess the efficacy and safety of hMSCs in long-term ex vivo expansion. In this study, we cultured...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipogenesis
Share to Cell Shape

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Transformation, Neoplastic

Share to Mesenchymal Stem Cells

Share to Mice, Nude

Share to Osteocytes

Share to Telomerase

Share to Telomere

Source

Identifiers

PMID: 19183884
DOI: 10.1007/s12272-009-1125-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Biological characterization of long-term cultured human mesenchymal stem cells.PMID 19183884Read ↗

Stabilization of cellular properties and differentiation mutilpotential of human mesenchymal stem cells transduced with hTERT gene in a long‐term cultureSemantic proximity Read ↗

Replicative Aging and Gene Expression in Long-Term Cultures of Human Bone Marrow Stromal CellsSemantic proximity Read ↗

Generation and Characterization of an Immortalized Human Mesenchymal Stromal Cell LineSemantic proximity Read ↗

Long-term cultures of bone marrow-derived human mesenchymal stem cells frequently undergo spontaneous malignant transformation.Semantic proximity Read ↗

Comparison of senescence phenotype of short- and long- term cultured rat mesenchymal stem cells in vitro.Semantic proximity Read ↗

Introducing a single‐cell‐derived human mesenchymal stem cell line expressing hTERT after lentiviral gene transferSemantic proximity Read ↗

Long-term cultured mesenchymal stem cells frequently develop genomic mutations but do not undergo malignant transformation.Semantic proximity Read ↗

Detection of spontaneous tumorigenic transformation during culture expansion of human mesenchymal stromal cellsSemantic proximity Read ↗

Phenotypic changes associated with continuous long term in vitro expansion of bone marrow-derived mesenchymal stem cells.Semantic proximity Read ↗

Human Umbilical Cord Matrix Stem Cells Maintain Multilineage Differentiation Abilities and Do Not Transform during Long-Term CultureSemantic proximity Read ↗

Immortalization without neoplastic transformation of human mesenchymal stem cells by transduction with HPV16 E6/E7 genes.Semantic proximity Read ↗

Molecular Basis of Immortalization of Human Mesenchymal Stem Cells by Combination of p53 Knockdown and Human Telomerase Reverse Transcriptase OverexpressionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.