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Replicative Aging and Gene Expression in Long-Term Cultures of Human Bone Marrow Stromal Cells

1 Dec 2002

Abstract excerpt

Bone marrow stromal cells (BMSCs) can be easily isolated from adult marrow and contain a population of pluripotent progenitors that can give rise to different mesenchymal lineages both in vitro and in vivo. These properties make BMSCs an attractive target for cell-based therapeutic strategies for a variety of disorders. However, because of their low frequency in vivo, to obtain a sufficient number of cells for...

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PMID: 12542936
DOI: 10.1089/107632702320934001

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