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Article

Higher susceptibility of NOG mice to xenotransplanted tumors.

The Journal of toxicological sciences - 1 Feb 2009

Machida Kazuhiko, Suemizu Hiroshi, Kawai Kenji, Ishikawa Tsuyoshi, Sawada Rumi, Ohnishi Yasuyuki, Tsuchiya Toshie

Abstract excerpt

The purpose of tumorigenicity testing, as applied not only to cell substrates used for viral vaccine manufacture but also stem cells used for cell-based therapy, is to discriminate between cells that have the capacity to form tumors and cells that do not. Therefore, tumorigenicity testing is essential in assessing the safety of these biological materials. Recently developed NOD/Shi-scid IL2Rg(null) (NOG) mice...

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Source

Identifiers

PMID: 19182442
DOI: 10.2131/jts.34.123

Genes

NOG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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