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Article

Mitochondrial DNA level, but not active replicase, is essential for Caenorhabditis elegans development.

Nucleic acids research - 1 Apr 2009

Bratic Ivana, Hench Jürgen, Henriksson Johan, Antebi Adam, Bürglin Thomas R, Trifunovic Aleksandra

Abstract excerpt

A number of studies showed that the development and the lifespan of Caenorhabditis elegans is dependent on mitochondrial function. In this study, we addressed the role of mitochondrial DNA levels and mtDNA maintenance in development of C. elegans by analyzing deletion mutants for mitochondrial po...

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Identifiers

PMID: 19181702
DOI: 10.1093/nar/gkp018
PMCID: PMC2665216

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19181702-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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