Article
Association of killer cell immunoglobulin-like receptors with primary Sjogren's syndrome.
Rheumatology (Oxford, England) - 1 Apr 2009
Lowe David P, Cook Mark A, Bowman Simon J, Briggs David C
Abstract excerpt
OBJECTIVE: SS is a chronic inflammatory condition characterized by systemic and tissue-specific autoimmune features. In view of recent findings indicating a role for killer cell immunoglobulin-like receptors (KIRs) in the pathogenesis of other autoimmune rheumatic disorders such as SSc, and the autoimmune disorders RA and PsA, we sought to determine whether KIRs predict general or specific susceptibility in SS....
Topics
- Case-Control Studies
- Chi-Square Distribution
- Female
- Gene Frequency
- Genotype
- HLA-C Antigens
- Heterozygote
- Humans
- Polymerase Chain Reaction
- Receptors, KIR
- Receptors, KIR2DL2