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Article

KIRs and autoimmune disease: studies in systemic lupus erythematosus and scleroderma.

Tissue antigens - 1 Apr 2007

Pellett F, Siannis F, Vukin I, Lee P, Urowitz M B, Gladman D D

Abstract excerpt

We investigated killer immunoglobulin-like receptors (KIRs) and the human leukocyte antigen (HLA)-C ligands for the corresponding inhibitory KIRs in Caucasian patients, 304 with systemic lupus erythematosus (SLE) and 90 with scleroderma [or progressive systemic sclerosis (PSS)] compared with 416 Caucasian controls. Compared with controls, KIR2DS1 in the absence of KIR2DS2 was increased in both SLE (P= 0.04) and...

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Identifiers

PMID: 17445179
DOI: 10.1111/j.1399-0039.2006.762_6.x

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