Article
Killer-cell immunoglobulin-like receptor gene polymorphisms and susceptibility to psoriatic arthritis.
Rheumatology (Oxford, England) - 1 Feb 2014
Chandran Vinod, Bull Shelley B, Pellett Fawnda J, Ayearst Renise, Pollock Remy A, Gladman Dafna D
Abstract excerpt
OBJECTIVES: We conducted a case-control study to determine the association between KIR2D and KIR3D gene polymorphisms and their interaction with HLA alleles in PsA. METHODS: A total of 678 subjects with PsA and 688 healthy controls were studied. Differences between cases and controls in the frequency of individual KIR polymorphisms were tested for significance by an asymptotic χ(2) test and Fisher's exact test....
Topics
- Adult
- Alleles
- Arthritis, Psoriatic
- Case-Control Studies
- Female
- Genetic Predisposition to Disease
- Genotype
- HLA-C Antigens
- Humans
- Male
- Middle Aged
