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Article

Fas and Fas ligand gene polymorphisms in primary Sjögren's syndrome.

The Journal of rheumatology - 1 Oct 2000

Bolstad A I, Wargelius A, Nakken B, Haga H J, Jonsson R

Abstract excerpt

OBJECTIVE: To screen for polymorphisms in the apoptosis regulating Fas and Fas ligand (FasL) genes in patients with primary Sjögren's syndrome (SS), and to explore associations with susceptibility to the disease. METHODS: Polymorphisms in Fas and FasL of 70 patients with primary SS and 72 controls were determined by polymerase chain reaction combined with the restriction enzyme fingerprinting single strand...

Topics

Adult
Aged
Aged, 80 and over
Apoptosis
DNA
DNA Fingerprinting
DNA Primers
Fas Ligand Protein
Female
Gene Frequency
Genetic Predisposition to Disease
Genetic Testing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Male

Membrane Glycoproteins

Middle Aged

Norway

Polymerase Chain Reaction

Source

Identifiers

PMID: 11036836

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