Genetic linkage findings for DSM-IV nicotine withdrawal in two populations.

doi:10.1002/ajmg.b.30924

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Article

Genetic linkage findings for DSM-IV nicotine withdrawal in two populations.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Oct 2009

Pergadia Michele L, Agrawal Arpana, Loukola Anu, Montgomery Grant W, Broms Ulla, Saccone Scott F, Wang Jen C, Todorov Alexandre A, Heikkilä Kauko, Statham Dixie J, Henders Anjali K, Campbell Megan J, Rice John P, Todd Richard D, Heath Andrew C, Goate Alison M, Peltonen Leena, Kaprio Jaakko, Martin Nicholas G, Madden Pamela A F

Abstract excerpt

Nicotine withdrawal (NW) is both an important contributor to difficulty quitting cigarettes and because of mood-related withdrawal symptoms a problem of particular relevance to psychiatry. Twin-studies suggest that genetic factors influence NW (heritability = 45%). Only one previous linkage study has published findings on NW [Swan et al. (2006); Am J Med Genet Part B 141B:354-360; LOD = 2.7; Chr. 6 at 159 cM]. As...

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PMID: 19180564
DOI: 10.1002/ajmg.b.30924
PMCID: PMC2995916

Genes

CHRNA10
DRD4

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