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Article

Human histamine N-methyltransferase pharmacogenetics: common genetic polymorphisms that alter activity.

Molecular pharmacology - 1 Apr 1998

Preuss C V, Wood T C, Szumlanski C L, Raftogianis R B, Otterness D M, Girard B, Scott M C, Weinshilboum R M

Abstract excerpt

Histamine N-methyltransferase (HNMT) catalyzes a major pathway in histamine metabolism. Levels of HNMT activity in humans are regulated by inheritance. We set out to study the molecular basis for this genetic regulation. Northern blot analysis showed that HNMT is highly expressed in the kidney, s...

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Identifiers

PMID: 9547362
DOI: 10.1124/mol.53.4.708

Genes

HNMT

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-9547362-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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