Article
[Expression of JAK2V617F and MPLW515L/K mutation in 30 suspected cases of early myeloproliferative disorders].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 1 Sept 2008
Fan Zheng, Zhang Ri, Shen Yi-Min, Fei Hai-Rong, Zhu Zi-Ling, Cen Jian-Nong
Abstract excerpt
OBJECTIVE: To investigate the prevalence of JAK2V617F and MPLW515L/K mutation in patients with slightly elevated platelets (BPC) or hemoglobin (Hb) not meeting the criteria of polycythemia vera (PV) or essential thrombocythemia (ET). METHODS: Genomic DNA from bone marrow or blood mononuclear cells was screened with allele specific polymerase chain reaction (AS-PCR) for JAK2V617F and MPLW515L/K mutation. The...
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