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Article

MPL mutations in myeloproliferative disorders: analysis of the PT-1 cohort.

Blood - 1 Jul 2008

Beer Philip A, Campbell Peter J, Scott Linda M, Bench Anthony J, Erber Wendy N, Bareford David, Wilkins Bridget S, Reilly John T, Hasselbalch Hans C, Bowman Richard, Wheatley Keith, Buck Georgina, Harrison Claire N, Green Anthony R

Abstract excerpt

Activating mutations of MPL exon 10 have been described in a minority of patients with idiopathic myelofibrosis (IMF) or essential thrombocythemia (ET), but their prevalence and clinical significance are unclear. Here we demonstrate that MPL mutations outside exon 10 are uncommon in platelet cDNA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18451306
DOI: 10.1182/blood-2008-01-131664

Genes

MPL
JAK2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18451306-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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MPL mutations in myeloproliferative disorders: analysis of the PT-1 cohort.PMID 18451306Read ↗

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