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Article

The association of JAK2V617F mutation and leukocytosis with thrombotic events in essential thrombocythemia.

Experimental hematology - 1 Nov 2007

Hsiao Hui-Hua, Yang Ming-Yu, Liu Yi-Chang, Lee Ching-Ping, Yang Wen-Chi, Liu Ta-Chih, Chang Chao-Sung, Lin Sheng-Fung

Abstract excerpt

OBJECTIVES: The Janus kinase 2 mutation, JAK2 (V617F), and megakaryocytic mutations, MPL (W515L/K), have been identified and correlated with a subtype of essential thrombocythemia (ET) patients. We investigated the frequency of mutations in ET patients and analyzed the relationship with their clinical features. METHODS: Fifty-three ET patients were enrolled in the study. The amplification refractory mutation...

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Source

Identifiers

PMID: 17920754
DOI: 10.1016/j.exphem.2007.08.011

Genes

JAK2
MPL

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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