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Article

Development of a cell-based assay for high-throughput screening of inhibitors against HCV genotypes 1a and 1b in a single well.

Antiviral research - 1 Apr 2009

Mondal Rubina, Koev Gennadiy, Pilot-Matias Tami, He Yupeng, Ng Teresa, Kati Warren, Molla Akhteruzzaman

Abstract excerpt

The Hepatitis C (HCV) replicon system is a useful tool for the high-volume screening of inhibitors of HCV replication. In this report, a cell-based assay has been described, which monitors the inhibition of HCV genotypes 1a and 1b as well as cytotoxicity, from a single well of a 96-well plate. A...

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Source

Identifiers

PMID: 19174175
DOI: 10.1016/j.antiviral.2008.12.012

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19174175-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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