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Article

Novel chimeric genotype 1b/2a hepatitis C virus suitable for high-throughput screening.

Antimicrobial agents and chemotherapy - 1 Feb 2008

Zhang Yingjia, Weady Peter, Duggal Rohit, Hao Weidong

Abstract excerpt

A major obstacle in hepatitis C virus (HCV) research has been the lack of a permissive cell culture system that produces infectious viral particles. Significant breakthroughs have been achieved lately in establishing such culture systems. Yet to date, there are no reports of the applications of any of these systems in HCV drug screening. Here, we report the generation of two monocistronic, chimeric genotype 1...

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Identifiers

PMID: 18039917
DOI: 10.1128/AAC.01133-07
PMCID: PMC2224717

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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