Article
Shared and specific susceptibility loci for schizophrenia and bipolar disorder: a dense genome scan in Eastern Quebec families.
Molecular psychiatry - 1 May 2005
Maziade M, Roy M-A, Chagnon Y C, Cliche D, Fournier J-P, Montgrain N, Dion C, Lavallée J-C, Garneau Y, Gingras N, Nicole L, Pirès A, Ponton A-M, Potvin A, Wallot H, Mérette C
Abstract excerpt
The goal of this study was to identify susceptibility loci shared by schizophrenia (SZ) and bipolar disorder (BP), or specific to each. To this end, we performed a dense genome scan in a first sample of 21 multigenerational families of Eastern Quebec affected by SZ, BP or both (N=480 family members). This probably constitutes the first genome scan of SZ and BP that used the same ascertainment, statistical and...
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