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Article

Effects of allicin on CYP2C19 and CYP3A4 activity in healthy volunteers with different CYP2C19 genotypes.

European journal of clinical pharmacology - 1 Jun 2009

Yang Li-Jun, Fan Lan, Liu Zhao-Qian, Mao Yan-Mei, Guo Dong, Liu Li-Hui, Tan Zhi-Rong, Peng Liang, Han Chun-Ting, Hu Dong-Li, Wang Dan, Zhou Hong-Hao

Abstract excerpt

OBJECTIVE: To investigate the interaction between allicin and omeprazole and to observe the effects of allicin on CYP2C19 and CYP3A4 activity in healthy Chinese male volunteers with different CYP2C19 genotypes. METHODS: Eighteen subjects (six CYP2C19*1/CYP2C19*1, four CYP2C19*1/CYP2C19*2, two CYP2C19*1/ CYP2C19*3, and six CYP2C19*2/ CYP2C19*2) were enrolled in a two-phase randomized crossover trial. In each...

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PMID: 19172254
DOI: 10.1007/s00228-008-0608-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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