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Article

A model for fine mapping in family based association studies.

Human heredity - 1 Jan 2009

Boehringer Stefan, Pfeiffer Ruth M

Abstract excerpt

Genome wide association studies for complex diseases are typically followed by more focused characterization of the identified genetic region. We propose a latent class model to evaluate a candidate region with several measured markers using observations on families. The main goal is to estimate linkage disequilibrium (LD) between the observed markers and the putative true but unobserved disease locus in the...

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PMID: 19172082
DOI: 10.1159/000194976

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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