Article
Abelson interactor-1 (ABI-1) interacts with MRL adaptor protein MIG-10 and is required in guided cell migrations and process outgrowth in C. elegans.
Developmental biology - 1 Jan 2013
McShea Molly A, Schmidt Kristopher L, Dubuke Michelle L, Baldiga Christina E, Sullender Meagan E, Reis Andrea L, Zhang Subaiou, O'Toole Sean M, Jeffers Mary C, Warden Rachel M, Kenney Allison H, Gosselin Jennifer, Kuhlwein Mark, Hashmi Sana K, Stringham Eve G, Ryder Elizabeth F
Abstract excerpt
Directed cell migration and process outgrowth are vital to proper development of many metazoan tissues. These processes are dependent on reorganization of the actin cytoskeleton in response to external guidance cues. During development of the nervous system, the MIG-10/RIAM/Lamellipodin (MRL) signaling proteins are thought to transmit positional information from surface guidance cues to the actin polymerization...
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