Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphisms in the genes encoding TGF-beta1, TNF-alpha, and IL-6 show association with type 1 diabetes mellitus in the Slovak population.

Archivum immunologiae et therapiae experimentalis - 1 Oct 2010

Javor Juraj, Ferencik Stanislav, Bucova Maria, Stuchlikova Martina, Martinka Emil, Barak Lubomir, Strbova Lujza, Grosse-Wilde Hans, Buc Milan

Abstract excerpt

Numerous cytokines have been shown to participate in the pathogenesis of type 1 diabetes (T1D). As gene polymorphisms can influence cytokine production or function, they may potentially contribute to genetic predisposition to the disease. The aim of this study was therefore to investigate the role of 22 single nucleotide polymorphisms (SNPs) in 13 cytokine and cytokine receptor genes in genetic susceptibility to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diabetes Mellitus, Type 1
Share to HLA-DR Antigens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HLA-DRB1 Chains

Share to Inflammation Mediators

Share to Interleukin-6

Share to Slovakia

Share to Transforming Growth Factor beta

Share to Tumor Necrosis Factor-alpha

Source

Identifiers

PMID: 20686866
DOI: 10.1007/s00005-010-0092-z

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms in the genes encoding TGF-beta1, TNF-alpha, and IL-6 show association with type 1 diabetes mellitus in the Slovak population.PMID 20686866Read ↗

The Influence of TNF-α, IL-6, TGF-β1, IFN-γ, IL-10 Polymorphisms on Predisposition to Diabetes Mellitus among Jordanian Patients.Semantic proximity Read ↗

Gene polymorphisms of TNF-alpha-308 (G/A), IL-10(-1082) (G/A), IL-6(-174) (G/C) and IL-1Ra (VNTR) in Egyptian cases with type 1 diabetes mellitus.Semantic proximity Read ↗

Association between cytokine genes polymorphisms and type 1 diabetes: a case-control study on Saudi population.Semantic proximity Read ↗

Association of a Large Panel of Cytokine Gene Polymorphisms with Complications and Comorbidities in Type 2 Diabetes Patients.Semantic proximity Read ↗

Association and interaction of the TNF-alpha gene with other pro- and anti-inflammatory cytokine genes and HLA genes in patients with type 1 diabetes from North India.Semantic proximity Read ↗

Cytokine gene variants of TNF-α and IL-10 in the propensity of type 2 diabetes in south Indian population.Semantic proximity Read ↗

Association of IL-6, TNF-α and IL-10 gene polymorphisms with type 2 diabetes mellitus.Semantic proximity Read ↗

Genomic Variants of Cytokine Associated With Development and Complication of Type 2 Diabetes in a Group of Turkish PopulationSemantic proximity Read ↗

Associations between TNF gene polymorphisms (-308 A/G, -238 A/G, -1031 C/T and -857 T/C) and genetic susceptibility to T1D: a meta-analysis.Semantic proximity Read ↗

Tumor necrosis factor-associated susceptibility to type 1 diabetes is caused by linkage disequilibrium with HLA-DR3 haplotypes.Semantic proximity Read ↗

Association between -308G/A TNFA Polymorphism and Susceptibility to Type 2 Diabetes Mellitus: A Systematic Review.Semantic proximity Read ↗

Association of TNF promoter polymorphisms with type 1 diabetes in the South Croatian population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.