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Article

Single amino acid sequence polymorphisms in rat cardiac troponin revealed by top-down tandem mass spectrometry.

Journal of muscle research and cell motility - 1 Jan 2008

Sancho Solis Raquel, Ge Ying, Walker Jeffery W

Abstract excerpt

Heterotrimeric cardiac troponin (cTn) is a critical component of the thin filament regulatory complex in cardiac muscle. Two of the three subunits, cTnI and cTnT, are subject to post-translational modifications such as proteolysis and phosphorylation, but linking modification patterns to function remains a major challenge. To obtain a global view of the biochemical state of cTn in native tissue, we performed high...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19165611
DOI: 10.1007/s10974-009-9168-y
PMCID: PMC3312389

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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