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Article

Association studies on ghrelin and ghrelin receptor gene polymorphisms with obesity.

Obesity (Silver Spring, Md.) - 1 Apr 2009

Gueorguiev Maria, Lecoeur Cécile, Meyre David, Benzinou Michael, Mein Charles A, Hinney Anke, Vatin Vincent, Weill Jacques, Heude Barbara, Hebebrand Johannes, Grossman Ashley B, Korbonits Márta, Froguel Philippe

Abstract excerpt

Ghrelin exerts a stimulatory effect on appetite and regulates energy homeostasis. Ghrelin gene variants have been shown to be associated with metabolic traits, although there is evidence suggesting linkage and association with obesity and the ghrelin receptor (GHSR). We hypothesized that these genes are good candidates for susceptibility to obesity. Direct sequencing identified 12 ghrelin single-nucleotide...

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Identifiers

PMID: 19165163
DOI: 10.1038/oby.2008.589

Genes

GHSR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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