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Article

A variation in the ghrelin gene increases weight and decreases insulin secretion in tall, obese children.

The Journal of clinical endocrinology and metabolism - 1 Aug 2002

Korbonits Márta, Gueorguiev Maria, O'Grady Eithne, Lecoeur Cecile, Swan Daniel C, Mein Charles A, Weill Jacques, Grossman Ashley B, Froguel Philippe

Abstract excerpt

Ghrelin is a recently recognized gut-brain peptide originally derived from the gastric mucosa. It stimulates growth hormone release, increases appetite and facilitates fat storage, and may interact with glucose metabolism. We studied the ghrelin gene in a group of 70 tall and obese children (mean age 9.4 year, Z body mass index [BMI] and Z height >3 and/or BMI percentile >99%). We found 10 single nucleotide...

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Identifiers

PMID: 12161552
DOI: 10.1210/jcem.87.8.8881

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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