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Article

Characterization of proteins associated with polyglutamine aggregates: a novel approach towards isolation of aggregates from protein conformation disorders.

Prion - 1 Jan 2000

Wang Yan, Meriin Anatoli B, Costello Catherine E, Sherman Michael Y

Abstract excerpt

The common feature of many neurodegenerative diseases is emergence of protein aggregates. Identifying their composition can provide valuable insights into the cellular mechanisms of protein aggregation and neuronal death. No reliable method for identification of the aggregate-associated proteins has been available. Here we describe a method for characterization of protein aggregates based on sedimentation of...

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Identifiers

PMID: 19164926
DOI: 10.4161/pri.1.2.4440
PMCID: PMC2634453

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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