Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An essential role for Radar (Gdf6a) in inducing dorsal fate in the zebrafish retina.

Proceedings of the National Academy of Sciences of the United States of America - 17 Feb 2009

Gosse Nathan J, Baier Herwig

Abstract excerpt

Retinal ganglion cells form orderly topographic connections with the tectum, establishing a continuous neural representation of visual space. Mapping along the dorsal-ventral axis requires interactions between EphB and ephrin-B cell-surface molecules expressed as countergradients in both retina and tectum. We have discovered that the diffusible TGFss-related factor Radar (Gdf6a) is necessary and sufficient for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Axons
Share to Body Patterning
Share to Cell Lineage

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Codon, Terminator

Share to Retina

Share to Transforming Growth Factor beta

Share to Zebrafish

Share to Zebrafish Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 19164594
DOI: 10.1073/pnas.0803202106
PMCID: PMC2650138

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An essential role for Radar (Gdf6a) in inducing dorsal fate in the zebrafish retina.PMID 19164594Read ↗

Radar breaks the fog: insights into dorsoventral patterning in zebrafish.Semantic proximity Read ↗

Pax6 interacts with cVax and Tbx5 to establish the dorsoventral boundary of the developing eye.Semantic proximity Read ↗

Morphogenetic movements underlying eye field formation require interactions between the FGF and ephrinB1 signaling pathways.Semantic proximity Read ↗

Meis1 specifies positional information in the retina and tectum to organize the zebrafish visual system.Semantic proximity Read ↗

Shootin-1 is required for nervous system development in zebrafish.Semantic proximity Read ↗

Xenopus Pax-6 and retinal development.Semantic proximity Read ↗

Xenopus mutant reveals necessity of rax for specifying the eye field which otherwise forms tissue with telencephalic and diencephalic character.Semantic proximity Read ↗

Pax6 induces ectopic eyes in a vertebrate.Semantic proximity Read ↗

Signaling circuitries in development: insights from the retinal determination gene network.Semantic proximity Read ↗

Functional mode of FoxD1/CBF2 for the establishment of temporal retinal specificity in the developing chick retina.Semantic proximity Read ↗

Extraocular ectoderm triggers dorsal retinal fate during optic vesicle evagination in zebrafish.Semantic proximity Read ↗

Ocular coloboma and dorsoventral neuroretinal patterning defects in Lrp6 mutant eyes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.