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Article

Pax6 induces ectopic eyes in a vertebrate.

Development (Cambridge, England) - 1 Oct 1999

Chow R L, Altmann C R, Lang R A, Hemmati-Brivanlou A

Abstract excerpt

We report here that misexpression of the transcription factor Pax6 in the vertebrate Xenopus laevis leads to the formation of differentiated ectopic eyes. Multiple molecular markers indicated the presence of mature lens fiber cells, ganglion cells, Müller cells, photoreceptors and retinal pigment...

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Source

Identifiers

PMID: 10477290
DOI: 10.1242/dev.126.19.4213

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-10477290-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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