Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Physical and functional interactions of the Arf tumor suppressor protein with nucleophosmin/B23.

Molecular and cellular biology - 1 Feb 2004

Bertwistle David, Sugimoto Masataka, Sherr Charles J

Abstract excerpt

The Arf tumor suppressor inhibits cell cycle progression through both p53-dependent and p53-independent mechanisms, including interference with rRNA processing. Using tandem-affinity-tagged p19(Arf), we purified Arf-associated proteins from mouse NIH 3T3 fibroblasts undergoing cell cycle arrest. Tagged p19(Arf) associated with nucleolar and ribosomal proteins, including nucleophosmin/B23 (NPM), a protein thought...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genes, Reporter
Share to Mice
Share to Mutation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Nuclear Proteins

Share to Protein Binding

Share to Ribosomes

Share to RNA, Ribosomal

Share to Transfection

Source

Open in PubMed Open full text

Identifiers

PMID: 14729947
DOI: 10.1128/MCB.24.3.985-996.2004
PMCID: PMC321449

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Physical and functional interactions of the Arf tumor suppressor protein with nucleophosmin/B23.PMID 14729947Read ↗

Cooperative signals governing ARF-mdm2 interaction and nucleolar localization of the complex.Semantic proximity Read ↗

B23 and ARF: friends or foes?Semantic proximity Read ↗

Nucleolar Arf tumor suppressor inhibits ribosomal RNA processing.Semantic proximity Read ↗

Myeloid Leukemia-Associated Nucleophosmin Mutants Perturb p53-Dependent and Independent Activities of the Arf Tumor Suppressor ProteinSemantic proximity Read ↗

Small mitochondrial Arf (smArf) protein corrects p53-independent developmental defects of Arf tumor suppressor-deficient mice.Semantic proximity Read ↗

DNA Damage Disrupts the p14ARF-B23(Nucleophosmin) Interaction and Triggers a Transient Subnuclear Redistribution of p14ARFSemantic proximity Read ↗

Delocalization and destabilization of the Arf tumor suppressor by the leukemia-associated NPM mutant.Semantic proximity Read ↗

N-terminal polyubiquitination and degradation of the Arf tumor suppressor.Semantic proximity Read ↗

Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2Semantic proximity Read ↗

Sumoylation induced by the Arf tumor suppressor: a p53-independent function.Semantic proximity Read ↗

Arf-induced turnover of the nucleolar nucleophosmin-associated SUMO-2/3 protease Senp3Semantic proximity Read ↗

NPM1/B23: A Multifunctional Chaperone in Ribosome Biogenesis and Chromatin RemodelingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.