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Article

Signal peptide peptidase- and ClpP-like proteins of Bacillus subtilis required for efficient translocation and processing of secretory proteins.

The Journal of biological chemistry - 27 Aug 1999

Bolhuis A, Matzen A, Hyyryläinen H L, Kontinen V P, Meima R, Chapuis J, Venema G, Bron S, Freudl R, van Dijl J M

Abstract excerpt

Signal peptides direct the export of secretory proteins from the cytoplasm. After processing by signal peptidase, they are degraded in the membrane and cytoplasm. The resulting fragments can have signaling functions. These observations suggest important roles for signal peptide peptidases. The present studies show that the Gram-positive eubacterium Bacillus subtilis contains two genes for proteins, denoted SppA...

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Identifiers

PMID: 10455123
DOI: 10.1074/jbc.274.35.24585

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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