Article
Replication of reported genetic associations of PADI4, FCRL3, SLC22A4 and RUNX1 genes with rheumatoid arthritis: results of an independent Japanese population and evidence from meta-analysis of East Asian studies.
Journal of human genetics - 1 Jan 2008
Takata Yoichiro, Inoue Hiroshi, Sato Aya, Tsugawa Kazue, Miyatake Katsutoshi, Hamada Daisuke, Shinomiya Fumio, Nakano Shunji, Yasui Natsuo, Tanahashi Toshihito, Itakura Mitsuo
Abstract excerpt
We conducted population-based association tests for the four selected SNPs (rs2240340/padi4_94, rs7528684/fcrl3_3, rs3792876/slc2F2 and rs2268277/runx1) previously reported to be associated with rheumatoid arthritis (RA). The study population consisted of 950 unrelated Japanese subjects with RA and 507 controls, none of whom had previously been tested for these variants. Only the SNP rs2240340/padi4_94 was...