Article
Reduced Tolerogenic Program Death-Ligand 1 (PD-L1)-expressed Conventional Type 1 Dendritic cells (cDC1) Is Associated with A Rapid Decliner Phenotype of Chronic Obstructive Pulmonary Disease (COPD)
2024-03-15
Abstract excerpt
<h4>Background: </h4> Chronic obstructive pulmonary disease (COPD) is characterized, at least in part, by autoimmunity through amplified T helper 1 and 17 (Th1 and Th17) immune response. Loss of immune tolerance controlled by programed death ligand 1 (PD-L1) may contribute to it <h4>Objectives: </h4> We studied the tolerogenic role of PD-L1+dendritic cells (DCs) and its subtypes in relation to specific T cell imm...
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Identifiers and source
- Literature Corpus work
- fcb183a0-41ee-56b9-add0-ef2fe62a16c1
- DOI
- 10.21203/rs.3.rs-4056864/v1
