Article
Characterization of myeloid and plasmacytoid dendritic cells in human lung.
Journal of immunology (Baltimore, Md. : 1950) - 1 Dec 2006
Masten Barbara J, Olson Gwyneth K, Tarleton Christy A, Rund Chad, Schuyler Mark, Mehran Reza, Archibeque Tereassa, Lipscomb Mary F
Abstract excerpt
Dendritic cells (DCs) are bone marrow-derived mononuclear cells that play a central role in the initiation of immune responses. Because human lung DCs have been incompletely characterized, we enumerated and phenotyped mononuclear cell populations from excess lung tissue obtained at surgery. Myeloid DCs (MDCs) were identified as CD1c(+)CD11c(+)CD14(-)HLA-DR(+) cells and comprised approximately 2% of low...
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