The endothelial nitric oxide synthase -786 T>C polymorphism and the exercise-induced blood pressure and nitric oxide responses among men with elevated blood pressure.

doi:10.1016/j.atherosclerosis.2008.12.015

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Article

The endothelial nitric oxide synthase -786 T>C polymorphism and the exercise-induced blood pressure and nitric oxide responses among men with elevated blood pressure.

Atherosclerosis - 1 Jun 2009

Augeri Amanda L, Tsongalis Gregory J, Van Heest Jaci L, Maresh Carl M, Thompson Paul D, Pescatello Linda S

Abstract excerpt

OBJECTIVE: A polymorphism (-786 T>C) in the promoter region of the endothelial nitric oxide synthase gene (eNOS) has important functional characteristics. We examined the influence of eNOS -786 T>C (rs2070744) on the BP and NO response to acute dynamic exercise. METHODS: Subjects (n=49, 43.7+/-1.4 yr) had pre- to Stage-1 hypertension (145.6+/-1.5/85.9+/-1.1 mmHg). Volunteers performed three experiments; a...

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PMID: 19155013
DOI: 10.1016/j.atherosclerosis.2008.12.015

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