Article
The presence of the NOS3 gene polymorphism for intron 4 mitigates the beneficial effects of exercise training on ambulatory blood pressure monitoring in adults.
American journal of physiology. Heart and circulatory physiology - 15 Jun 2014
Sponton Carlos H, Esposti Rodrigo, Rodovalho Cynara M, Ferreira Maycon J, Jarrete Aline P, Anaruma Chadi P, Bacci Mauricio, Zanesco Angelina
Abstract excerpt
The number of studies that have evaluated exercise training (ET) and nitric oxide synthase (NOS)3 gene polymorphisms is scarce. The present study was designed to evaluate the relationship between exercise training and NOS3 polymorphisms at -786T>C, 894G>T, and intron 4b/a on blood pressure (BP) using 24-h ambulatory BP monitoring (ABPM), nitrate/nitrite levels (NOx), and redox state. Eighty-six volunteers (51 ±...
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