Article
Relation of endothelial nitric oxide synthase gene to plasma nitric oxide level, endothelial function, and blood pressure in African Americans.
American journal of hypertension - 1 Jul 2004
Li Rongling, Lyn Deborah, Lapu-Bula Rigobert, Oduwole Adefisayo, Igho-Pemu Priscilla, Lankford Brenda, Morgan Jan, Nkemdechi Sunday, Liu Gang, Pack Cheryl, Silvestrov Natalia, von Deutsch Daniel A, Song Qing, Abukhalaf Imad K, Ofili Elizabeth
Abstract excerpt
BACKGROUND: The role of eNOS gene polymorphisms on plasma nitrite or nitrate (NOx) level, endothelial function, and blood pressure (BP) remains unclear. METHODS: We estimated the relationship of eNOS polymorphisms (the T(-786)C in the 5'-flanking promoter region, T(-786)C; 27-bp repeat in intron 4, eNOS4; and Glu298Asp in exon 7, G894T) with plasma NOx level, brachial endothelial function assessed by ultrasound...
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