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Article

Impact of psychosocial adversity on alcohol intake in young adults: moderation by the LL genotype of the serotonin transporter polymorphism.

Biological psychiatry - 15 Jul 2009

Laucht Manfred, Treutlein Jens, Schmid Brigitte, Blomeyer Dorothea, Becker Katja, Buchmann Arlette F, Schmidt Martin H, Esser Günter, Jennen-Steinmetz Christine, Rietschel Marcella, Zimmermann Ulrich S, Banaschewski Tobias

Abstract excerpt

BACKGROUND: Evidence from animal studies supports a role for serotonin transporter gene promoter polymorphism (5-HTTLPR) gene-environment interaction (G x E) in the development of excessive alcohol intake. Few studies in humans have been conducted on this topic, yielding inconsistent results. The present study aims to further explore G x E between 5-HTTLPR and exposure to psychosocial adversity on alcohol...

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Identifiers

PMID: 19358979
DOI: 10.1016/j.biopsych.2009.02.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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