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Article

Damage recognition by UV damage endonuclease from Schizosaccharomyces pombe.

DNA repair - 1 May 2009

Paspaleva Keti, Moolenaar Geri F, Goosen Nora

Abstract excerpt

UV damage endonuclease (UVDE) from Schizosaccharomyces pombe initiates repair of UV lesions and abasic sites by nicking the DNA 5' to the damaged site. In this paper we show that in addition UVDE incises DNA containing a single-strand nick or gap, but that the enzymatic activity on these substrates as well as on abasic sites strongly depends on the presence of a neighbouring pyrimidine residue. This indicates...

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Identifiers

PMID: 19152795
DOI: 10.1016/j.dnarep.2008.12.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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