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Article

AP endonuclease independent repair of abasic sites in Schizosaccharomyces pombe.

Nucleic acids research - 1 Mar 2012

Nilsen Line, Forstrøm Rune J, Bjørås Magnar, Alseth Ingrun

Abstract excerpt

Abasic (AP) sites are formed spontaneously and are inevitably intermediates during base excision repair of DNA base damages. AP sites are both mutagenic and cytotoxic and key enzymes for their removal are AP endonucleases. However, AP endonuclease independent repair initiated by DNA glycosylases performing β,δ-elimination cleavage of the AP sites has been described in mammalian cells. Here, we describe another AP...

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Identifiers

PMID: 22084197
DOI: 10.1093/nar/gkr933
PMCID: PMC3300018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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