Article
Characterization of the alternative excision repair pathway of UV-damaged DNA in Schizosaccharomyces pombe.
Nucleic acids research - 15 Apr 1997
Yonemasu R, McCready S J, Murray J M, Osman F, Takao M, Yamamoto K, Lehmann A R, Yasui A
Abstract excerpt
Schizosaccharomyces pombe cells deficient in nucleotide excision repair (NER) are still able to remove photoproducts from cellular DNA, showing that there is a second pathway for repair of UV damage in this organism. We have characterized this repair pathway by cloning and disruption of the genomic gene encoding UV damage endonuclease (UVDE). Although uvde gene disruptant cells are only mildly UV sensitive, a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.