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Vitamin D Receptor Gene Polymorphism: An Important Predictor of Arthritis Development

18 Mar 2019

Abstract excerpt

Vitamin D is an anti-inflammatory molecule and has a role in prevention of arthritis development. Biologically active form 1, 25(OH)2D3 of vitamin D can only exert its action after binding its definite vitamin D receptor encoded by VDR gene. VDR gene polymorphism leads to dysfunctioning of 1, 25(OH)2D3 ultimately disease onset. The purpose of current study was to evaluate the effect of vitamin D level and VDR...

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PMID: 31011579
DOI: 10.1155/2019/8326246

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