Article
No association between a functional polymorphism in the promoter region of the neuropeptide Y gene (-485C>T) and schizophrenia.
Neuroscience letters - 6 Mar 2009
Inoue Yoshiaki, Shinkai Takahiro, Utsunomiya Kensuke, Sakata Shinichi, Fukunaka Yuko, Yamaguchi Wakana, Yamada Kenji, Chen Hsin-I, Hwang Rudi, Ohmori Osamu, Nakamura Jun
Abstract excerpt
It has been suggested that hypoactivity of neuropeptide Y (NPY) may be involved in the pathophysiology of schizophrenia. A post-mortem study revealed a decreased level of NPY in the brain of patients with schizophrenia. An increased level of NPY after antipsychotic treatment was also reported in animal brain and cerebrospinal fluid of patients. Previously Itokawa et al. reported a positive association between the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.