Case-control association study of the 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP) gene and schizophrenia in the Han Chinese population.

doi:10.1016/j.neulet.2007.01.054

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Case-control association study of the 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP) gene and schizophrenia in the Han Chinese population.

Neuroscience letters - 12 Apr 2007

Tang Fulei, Qu Mei, Wang Lifang, Ruan Yan, Lu Tianlan, Zhang Handi, Liu Zhonghua, Yue Weihua, Zhang Dai

Abstract excerpt

Converging evidence from imaging, microarray, genetic, and other studies suggests that abnormalities in myelin may play a role in schizophrenia. The expression of 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP), which is used as a myelin marker, has been reported to be reduced in the schizophrenic brain. A synonymous genetic variation in the CNP gene, rs2070106, has recently been shown to be associated with...

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PMID: 17306456
DOI: 10.1016/j.neulet.2007.01.054

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