Article
CHRFAM7A copy number and 2-bp deletion polymorphisms and antisaccade performance.
The international journal of neuropsychopharmacology - 1 Mar 2009
Petrovsky Nadine, Schmechtig Anne, Flomen Rachel H, Kumari Veena, Collier David, Makoff Andrew, Wagner Michael, Ettinger Ulrich
Abstract excerpt
Chromosome 15q13-q14 harbours the gene for the alpha7 nicotinic acetylcholine receptor subunit (CHRNA7) and a related gene (CHRFAM7A) which arises from a partly duplicated portion of CHRNA7. Recent evidence suggests that CHRFAM7A is a locus with a possible role in schizophrenia and cognitive functioning. We studied an antisaccade task as a fronto-parietal measure of executive function that reflects risk for...
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